In England, liver cirrhosis (resulting from alcoholic and non-alcoholic chronic hepatitis) was reported to account for 51% of all deaths within one year of admission from 1979-1998 3. The Centre for Disease Control (CDC) had in 1998, listed CLD as the tenth leading cause of death in the United States of America 2. Conclusion: The C-P and MELD scores are valid predictors of short-term mortality from CLD irrespective of aetiology, however, the MELD performed better than the C-P score.Ĭhronic liver disease (CLD) is a major world health problem with a high mortality rate 1. It was superior to that of C-P score which was 0.777 (95% CI 0.689-0.864). In multivariate analysis, the MELD and C-P scores were both independent predictors of 3-month mortality(p<.001). HCC and liver cirrhosis comprised 48(69%) and 22(31%) of the non-survivors and both were associated with mortality (p=0.000). Of those who completed the study, 70(66%) died and 36(34%) survived. Only 106 patients completed the study while 6 were lost to follow-up. Results: Of the 112 patients recruited into the study, 60(54%) had HCC, 46(41%) had liver cirrhosis and 6(5%) had chronic hepatitis. The C-P as well as the MELD score of each patient was calculated on enrolment. A total of 112 subjects with CLD were recruited from September 2007 to May 2008 and were followed-up for three months to determine outcome (death or survival) at the end of this period. Method: This was a prospective study in two hospitals in Anambra state, Nigeria. We aimed to compare the predictability values of these scores in determining short-term mortality in a cohort of CLD patients in Anambra state, South-east, Nigeria. The Child-Pugh’s (C-P) and Model for end-stage liver disease (MELD) scores are important determinants of severity and prognosis in CLD. Open cholecystectomy is associated with significantly more morbidity and mortality than laparoscopic cholecystectomy across all MELD groups.Īscites Cholecystectomy Cirrhosis MELD Model for end-stage liver disease NSQIP.Background: Chronic liver disease (CLD) is a major cause of morbidity and mortality worldwide with differing aetiology in different geographic regions. Patients with ascites have substantially worse outcomes across all MELD scores. The MELD score is an objective and easy to calculate scoring system that independently predicts postoperative morbidity and mortality in patients undergoing cholecystectomy.

After adjustment, MELD score acted as a progressive and independent predictor of morbidity and mortality. Bivariate data analysis was performed and logistic regression modeling was conducted to calculate risk-adjusted 30-day outcomes.Ī total of 63,464 patients were included in the study. Patients were excluded if they had choledocholithiasis or preoperative dialysis. The American College of Surgeons National Surgical Quality Improvement Program database from 2005 to 2013 was used to study patients undergoing cholecystectomy.

The magnitude of risk for patients undergoing cholecystectomy with high model for end-stage liver disease (MELD) scores is poorly understood.

Meld score mortality